Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50006741
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052975(Methyl-[2-(4-nitro-phenyl)-ethyl]-(2-pyrrolidin-1-...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052965(Methyl-[2-(3-nitro-phenyl)-ethyl]-(2-pyrrolidin-1-...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052968(Methyl-[2-(2-nitro-phenyl)-ethyl]-(2-pyrrolidin-1-...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052966([2-(2-Methoxy-phenyl)-ethyl]-methyl-(2-pyrrolidin-...)
Affinity DataKi:  15.7nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052964([2-(3-Methoxy-phenyl)-ethyl]-methyl-(2-pyrrolidin-...)
Affinity DataKi:  23.8nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052971([2-(4-Methoxy-phenyl)-ethyl]-methyl-(2-pyrrolidin-...)
Affinity DataKi:  30.3nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052967(4-{2-[Methyl-(2-pyrrolidin-1-yl-ethyl)-amino]-ethy...)
Affinity DataKi:  276nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052977(2-{2-[Methyl-(2-pyrrolidin-1-yl-ethyl)-amino]-ethy...)
Affinity DataKi:  291nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052969(3-{2-[Methyl-(2-pyrrolidin-1-yl-ethyl)-amino]-ethy...)
Affinity DataKi:  579nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052973(N-Methyl-2-(2-nitro-phenyl)-N-(2-pyrrolidin-1-yl-e...)
Affinity DataKi:  736nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052976(N-Methyl-2-(4-nitro-phenyl)-N-(2-pyrrolidin-1-yl-e...)
Affinity DataKi:  869nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052972(N-Methyl-2-(3-nitro-phenyl)-N-(2-pyrrolidin-1-yl-e...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052974(2-(4-Methoxy-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl...)
Affinity DataKi:  2.22E+3nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052970(2-(3-Methoxy-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50052963(2-(2-Methoxy-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl...)
Affinity DataKi:  5.46E+3nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma opioid receptor type 1 in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed