Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 1202
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9948((8R)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  4.70nM ΔG°:  -49.4kJ/mole IC50: 54nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9951((8R)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  5nM ΔG°:  -49.3kJ/mole IC50: 54nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9949((8R)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  7nM ΔG°:  -48.4kJ/mole IC50: 60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9953((8R)-8-heptyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  7.80nM ΔG°:  -48.1kJ/mole IC50: 60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9952((8R)-8-hexyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  8nM ΔG°:  -48.1kJ/mole IC50: 76nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9944((8S)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/mole IC50: 140nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9950((8R)-8-butyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  14nM ΔG°:  -46.6kJ/mole IC50: 180nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9943((8S)-8-butyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/mole IC50: 200nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9941((8S)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  19nM ΔG°:  -45.8kJ/mole IC50: 250nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9946((8S)-8-heptyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/mole IC50: 250nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM8592([1beta-3H] androstenedione | 4-Androsten-3,17-dion...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/mole IC50: 300nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9942((8S)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  22nM ΔG°:  -45.5kJ/mole IC50: 270nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9945((8S)-8-hexyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  25nM ΔG°:  -45.1kJ/mole IC50: 280nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9947((8R)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  43nM ΔG°:  -43.7kJ/mole IC50: 520nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9954(2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]he...)
Affinity DataKi:  43nM ΔG°:  -43.7kJ/mole IC50: 530nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9940((8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  54nM ΔG°:  -43.2kJ/mole IC50: 620nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed