Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50006421
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048893((2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-2-methyl-1,...)
Affinity DataKi:  2.60nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048891((3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-...)
Affinity DataKi:  8.10nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048892((2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-2-methyl-1,...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048895((2S,3R,11bR)-2,3-Diisobutyl-9,10-dimethoxy-1,3,4,6...)
Affinity DataKi:  33nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048897((2S,3R,11bR)-2-Ethyl-3-isobutyl-9,10-dimethoxy-1,3...)
Affinity DataKi:  42nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048894((2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-2-propyl-1,...)
Affinity DataKi:  84nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50048896((2S,3R,11bR)-2-tert-Butyl-3-isobutyl-9,10-dimethox...)
Affinity DataKi:  136nMAssay Description:In vitro inhibition of [3H]- Methoxytetrabenazine binding to rat brain vesicular monoamine transporter 2 (VMAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed