Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50048906
TargetSerotonin 2 (5-HT2) receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKd:  13nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKd:  501nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKd:  1.58E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor in piglet choroid plexus using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKd:  5.01E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor in piglet choroid plexus using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKd: >5.01E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1D(Pig)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKd:  25nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor in piglet caudate using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKd:  32nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKd:  631nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKd:  3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Pig)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKd:  10nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor in piglet caudate using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKd:  0.316nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed