Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50006313
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047471(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 16nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 24nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047472(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 34nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 265nMAssay Description:In vitro binding affinity towards the dopamine receptor D2 at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50456023(CHEMBL289981)
Affinity DataIC50: 437nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the noradrenergic beta receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the noradrenergic alpha-2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1C receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the noradrenergic alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047471(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 1.39E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047472(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 1.49E+3nMAssay Description:In vitro binding affinity towards the anor-adrenergic alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50047471(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 1.88E+3nMAssay Description:In vitro binding affinity towards the alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 2.15E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth Research (Uk)

Curated by ChEMBL
LigandPNGBDBM50456023(CHEMBL289981)
Affinity DataIC50: 2.78E+3nMAssay Description:In vitro binding affinity towards the noradrenergic alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed