Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50006268
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011228((R)-2-Benzyl-N-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-...)
Affinity DataIC50: 1.30nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022647(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046785(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 2.80nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046781(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 3.5nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046786(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 5.40nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011231(CHEMBL344272 | 2-Benzyl-N-{1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 8.10nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006122(CHEMBL49862 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2,...)
Affinity DataIC50: 8.30nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046782(N-[2-Azido-1-(1-cyclohexylmethyl-2,3-dihydroxy-5-m...)
Affinity DataIC50: 11nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006202(A-64662 | CHEMBL300337 | 3-Amino-N-[1-[1-(1-cycloh...)
Affinity DataIC50: 14nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046773(3-Amino-N-[1-[1-[1-cyclohexylmethyl-2-(3-ethyl-2-o...)
Affinity DataIC50: 17nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046776(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 18nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046774(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 18nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011229(CHEMBL342864 | 2-Benzyl-N-[1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 21nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046778(2-Benzyl-5-morpholin-4-yl-4-oxo-pentanoic acid [1-...)
Affinity DataIC50: 25nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046770(2-[2-Benzyl-4-(4-methyl-piperazin-1-yl)-4-oxo-buty...)
Affinity DataIC50: 25nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046779(3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 33nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046783(2-[2-Benzyl-4-(4-methyl-piperazin-1-yl)-4-oxo-buty...)
Affinity DataIC50: 37nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046784(3-Amino-N-[1-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-o...)
Affinity DataIC50: 39nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011227(CHEMBL341975 | 2-Benzyl-N-{1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 43nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011230(CHEMBL262306 | 2-Benzyl-N-[1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 58nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046771(3-Amino-N-[1-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-o...)
Affinity DataIC50: 69nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046780(3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 85nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046790(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 88nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046788(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 93nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046789(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046777(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046787(4-Methyl-piperazine-1-carboxylic acid [1-[1-(1-cyc...)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046775(1-Methyl-piperidine-4-carboxylic acid [1-[1-(1-cyc...)
Affinity DataIC50: 170nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046772(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50: 210nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046791(N-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-he...)
Affinity DataIC50: 1.60E+3nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed