Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50005971
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043224BDBM50043224(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043221BDBM50043221(3-Mercapto-6-methyl-4-(1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043231BDBM50043231(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043228BDBM50043228(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043227BDBM50043227(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 10nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043237BDBM50043237(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 12nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043222BDBM50043222(4-(2-Benzyloxy-1-methylcarbamoyl-propylcarbamoyl)-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043222BDBM50043222(4-(2-Benzyloxy-1-methylcarbamoyl-propylcarbamoyl)-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043235BDBM50043235(2-(1-Mercapto-ethyl)-4-methyl-pentanoic acid [2-(4...)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043242BDBM50043242(3-Acetylsulfanyl-4-[2-(1H-indol-3-yl)-1-methylcarb...)
Affinity DataIC50: 19nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043231BDBM50043231(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenase without beta-mercaptoethanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043223BDBM50043223(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 22nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043238BDBM50043238(2-Isobutyl-3-mercapto-pentanedioic acid 5-amide 1-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043230BDBM50043230(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 25nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043229BDBM50043229({3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbam...)
Affinity DataIC50: 27nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043243BDBM50043243(2-Isobutyl-3-mercapto-pentanedioic acid 5-carbamoy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043232BDBM50043232(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 34nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043220BDBM50043220(3-Acetylsulfanyl-4-[2-(4-methoxy-phenyl)-1-methylc...)
Affinity DataIC50: 44nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043224BDBM50043224(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 68nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenase without beta-mercaptoethanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043225BDBM50043225(2-Isobutyl-3-mercapto-5-(4-methyl-piperazin-1-yl)-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043234BDBM50043234(2-Isobutyl-3-mercapto-pentanedioic acid 1-{[2-(4-m...)
Affinity DataIC50: 145nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043233BDBM50043233(4-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-mercapto...)
Affinity DataIC50: 190nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043233BDBM50043233(4-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-mercapto...)
Affinity DataIC50: 190nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043240BDBM50043240({3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbam...)
Affinity DataIC50: 280nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043226BDBM50043226(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 730nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043226BDBM50043226(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 730nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043236BDBM50043236(2-{3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarb...)
Affinity DataIC50: 830nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043239BDBM50043239(2-{3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarb...)
Affinity DataIC50: 980nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043241BDBM50043241(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 980nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043241BDBM50043241(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Affinity DataIC50: 980nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043223BDBM50043223(4-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenase without beta-mercaptoethanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed