Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50005969
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50008413(CHEMBL262984 | 8-(1-Methyl-2-phenyl-ethyl)-1,3-dip...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043209(8-(1-Phenyl-propyl)-1,3-dipropyl-3,9-dihydro-purin...)
Affinity DataKi:  23.2nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043214(8-(1-Phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine...)
Affinity DataKi:  25.3nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50011216(CHEMBL337073 | 1-Methyl-8-(1-methyl-2-phenyl-ethyl...)
Affinity DataKi:  32.6nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50011222(8-(1-Phenyl-propyl)-1,3-dipropyl-3,9-dihydro-purin...)
Affinity DataKi:  33.5nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043212(8-(1-Phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine...)
Affinity DataKi:  49.4nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043210(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihyd...)
Affinity DataKi:  60.7nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50005376(8-Indan-2-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  64.3nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043208(8-(1-Benzyl-butyl)-1,3-dipropyl-3,9-dihydro-purine...)
Affinity DataKi:  73.8nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043206(8-(2-Phenyl-propyl)-1,3-dipropyl-3,9-dihydro-purin...)
Affinity DataKi:  94.3nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043213(1,3-Dipropyl-8-(1,2,3,4-tetrahydro-naphthalen-2-yl...)
Affinity DataKi:  94.6nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043216(8-(1-Phenyl-propyl)-1,3-dipropyl-3,9-dihydro-purin...)
Affinity DataKi:  136nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043211(8-(1-Benzyl-propyl)-1,3-dipropyl-3,9-dihydro-purin...)
Affinity DataKi:  161nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043215(8-(2-Phenyl-cyclopentyl)-1,3-dipropyl-3,9-dihydro-...)
Affinity DataKi:  164nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043207(8-(1-Phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine...)
Affinity DataKi:  175nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043217(8-(1-Hydroxymethyl-2-phenyl-ethyl)-1,3-dipropyl-3,...)
Affinity DataKi:  1.29E+3nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed