Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50036190
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029050(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
Affinity DataEC50:  230nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042997(4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...)
Affinity DataEC50: >1.00E+5nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019057((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataEC50: >1.50E+3nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataEC50:  52nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50:  63nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019059(3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene...)
Affinity DataEC50:  40nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019057((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029050(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019059(3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021546(CHEMBL61372 | 4-Fluoro-3-(1-hydroxy-2-methylamino-...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM36024(PHENYLEPHRINE | Phenylephrine,(-) | (R)-(-)-phenyl...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019057((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataKi:  700nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042999(3,6-Difluoro-4-(1-hydroxy-2-methylamino-ethyl)-ben...)
Affinity DataKi:  710nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029050(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
Affinity DataKi:  720nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042997(4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...)
Affinity DataKi:  750nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042995(2,4-Difluoro-3-(1-hydroxy-2-methylamino-ethyl)-phe...)
Affinity DataKi:  940nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021545(CHEMBL302451 | 2-Fluoro-3-(1-hydroxy-2-methylamino...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042999(3,6-Difluoro-4-(1-hydroxy-2-methylamino-ethyl)-ben...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029050(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019059(3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021546(CHEMBL61372 | 4-Fluoro-3-(1-hydroxy-2-methylamino-...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042999(3,6-Difluoro-4-(1-hydroxy-2-methylamino-ethyl)-ben...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029050(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042996(4-(2-Amino-1-hydroxy-ethyl)-3,6-difluoro-benzene-1...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021545(CHEMBL302451 | 2-Fluoro-3-(1-hydroxy-2-methylamino...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042996(4-(2-Amino-1-hydroxy-ethyl)-3,6-difluoro-benzene-1...)
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM36024(PHENYLEPHRINE | Phenylephrine,(-) | (R)-(-)-phenyl...)
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM36024(PHENYLEPHRINE | Phenylephrine,(-) | (R)-(-)-phenyl...)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019059(3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene...)
Affinity DataKi:  1.65E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021545(CHEMBL302451 | 2-Fluoro-3-(1-hydroxy-2-methylamino...)
Affinity DataKi:  1.70E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042995(2,4-Difluoro-3-(1-hydroxy-2-methylamino-ethyl)-phe...)
Affinity DataKi:  1.70E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataKi:  2.30E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042996(4-(2-Amino-1-hydroxy-ethyl)-3,6-difluoro-benzene-1...)
Affinity DataKi:  2.40E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataKi:  2.90E+4nMAssay Description:Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50042999(3,6-Difluoro-4-(1-hydroxy-2-methylamino-ethyl)-ben...)
Affinity DataKi:  3.90E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataKi:  4.50E+4nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
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