Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50036321
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.115nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataKi:  0.121nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKd:  0.150nMAssay Description:The potency of the [3H]paroxetine for 5-HT transportersMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041304(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataKi:  0.394nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041308(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKd:  1nMAssay Description:The potency of the [125I]RTI-55 for Dopamine transporter siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041304(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041294(1-(3-Biphenyl-4-yl-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041294(1-(3-Biphenyl-4-yl-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(PTT(-) | CHEMBL23142 | 1-(8-Methyl-3-p-tolyl-8-aza...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(PTT(-) | CHEMBL23142 | 1-(8-Methyl-3-p-tolyl-8-aza...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041299(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041298(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041306(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataIC50: 15nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041298(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041297(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataIC50: 48nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041295(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataIC50: 71nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041307(1-[3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1...)
Affinity DataKi:  78nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041302(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataIC50: 114nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041299(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi:  122nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(PTT(-) | CHEMBL23142 | 1-(8-Methyl-3-p-tolyl-8-aza...)
Affinity DataKi:  131nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(PTT(-) | CHEMBL23142 | 1-(8-Methyl-3-p-tolyl-8-aza...)
Affinity DataKi:  131nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041307(1-[3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1...)
Affinity DataIC50: 152nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataIC50: 436nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041306(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  630nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041295(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  857nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041297(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataKi:  1.01E+3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041305(1-(8-Methyl-3-o-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041302(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041310(1-[3-(4-tert-Butyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041310(1-[3-(4-tert-Butyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041301(1-(3-Cyclohexyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2...)
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041305(1-(8-Methyl-3-o-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041309(1-(3-Ethyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041301(1-(3-Cyclohexyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041309(1-(3-Ethyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed