Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50005778
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040857((S)-2-{2-Fluoro-4-[(3-methyl-1-oxo-1,2-dihydro-ben...)
Affinity DataKi:  0.0900nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040861(S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZ...)
Affinity DataKi:  0.0900nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040865(TCMDC-137629 | (S)-2-{4-[(3-Methyl-1-oxo-1,2-dihyd...)
Affinity DataKi:  0.440nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040860((S)-2-({5-[(3-Methyl-1-oxo-1,2-dihydro-benzo[f]qui...)
Affinity DataKi:  1.10nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040863((S)-2-{4-[(3-Amino-1-oxo-1,2-dihydro-benzo[f]quina...)
Affinity DataKi:  1.20nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040859((S)-2-{5-[Methyl-(3-methyl-1-oxo-1,2-dihydro-benzo...)
Affinity DataKi:  2.5nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040862((S)-2-{6-[(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quin...)
Affinity DataKi:  4nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040858(2-[4-(3-Methyl-1-oxo-1,2-dihydro-benzo[f]quinazoli...)
Affinity DataKi:  5.5nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040864(TCMDC-138089 | (S)-2-{4-[Methyl-(3-methyl-1-oxo-1,...)
Affinity DataKi:  22nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase (purified recombinant human gene) from Escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed