Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50005735
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040371(1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-8-[...)
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040346(8-Amino-1,3-bis-cyclopropylmethyl-7-(4-methoxy-ben...)
Affinity DataIC50: 140nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040348(BRL-61063 | 8-Amino-1,3-bis-cyclopropylmethyl-3,7-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040379(N'-[1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)...)
Affinity DataIC50: 240nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040354(8-Amino-1,3-bis-cyclopropylmethyl-7-(3,4-dimethoxy...)
Affinity DataIC50: 300nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040356(8-Amino-1,3-bis-cyclopropylmethyl-7-(4-methoxy-ben...)
Affinity DataIC50: 440nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020874(CHEMBL332898 | (3-Chloro-phenyl)-(4-phenyl-phthala...)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase 5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040371(1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-8-[...)
Affinity DataIC50: 610nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040362(8-Amino-7-benzyl-1,3-bis-cyclopropylmethyl-3,7-dih...)
Affinity DataIC50: 840nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 900nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040372(8-Amino-7-(4-chloro-benzenesulfonyl)-1,3-bis-cyclo...)
Affinity DataIC50: 900nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040359(N-[1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040377(CHEMBL42713 | SK&F-96321 | SK-96321 | 2-(2-Propoxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of phosphodiesterase 5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040349(8-Amino-1,3-bis-cyclopropylmethyl-7-(toluene-4-sul...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040345(N-(1,3-Bis-cyclopropylmethyl-2,6-dioxo-2,3,6,7-tet...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040351(8-Amino-1,3-bis-cyclopropylmethyl-7-propyl-3,7-dih...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040359(N-[1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040355(1,3-Bis(cyclopropylmethyl)-8-bis[(4-nitrophenylsul...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040344(8-Amino-1,3-bis-cyclopropylmethyl-7-(propane-2-sul...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040362(8-Amino-7-benzyl-1,3-bis-cyclopropylmethyl-3,7-dih...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040350(8-Amino-1,3-bis-cyclopropylmethyl-7-methanesulfony...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040352(1,3-Bis-cyclopropylmethyl-8-[1-methyl-pyrrolidin-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040343(8-Amino-1,3-bis-cyclopropylmethyl-7-isobutyl-3,7-d...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040369(8-Amino-7-benzenesulfonyl-1,3-bis-cyclopropylmethy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040349(8-Amino-1,3-bis-cyclopropylmethyl-7-(toluene-4-sul...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040372(8-Amino-7-(4-chloro-benzenesulfonyl)-1,3-bis-cyclo...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040375(1,3-Bis(cyclopropylmethyl)-8-bis[(4-nitrophenylsul...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of phosphodiesterase 2 at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040376(1,3-Bis(cyclopropylmethyl)-8-bis[(phenylsulfonyl)a...)
Affinity DataIC50: 6.50E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040366(8-Amino-1,3-bis-cyclopropylmethyl-7-(4-nitro-benzy...)
Affinity DataIC50: 8.30E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040365(8-Amino-1,3-bis-cyclopropylmethyl-7-naphthalen-1-y...)
Affinity DataIC50: 9.80E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040358(5-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040343(8-Amino-1,3-bis-cyclopropylmethyl-7-isobutyl-3,7-d...)
Affinity DataIC50: 1.10E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of phosphodiesterase 1C at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040374(8-Amino-1,3-bis-cyclopropylmethyl-7-(3,4,5-trimeth...)
Affinity DataIC50: 1.30E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040351(8-Amino-1,3-bis-cyclopropylmethyl-7-propyl-3,7-dih...)
Affinity DataIC50: 1.40E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10847(Theophylline (1,3-dimethylxanthine) | 1,3-dimethyl...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040363(1,3-Bis(cyclopropylmethyl)-8-bis[(phenylsulfonyl)a...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040368(8-Amino-1,3-bis-cyclopropylmethyl-7-methyl-3,7-dih...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040357(N-(1,3-Bis-cyclopropylmethyl-2,6-dioxo-2,3,6,7-tet...)
Affinity DataIC50: 2.20E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040355(1,3-Bis(cyclopropylmethyl)-8-bis[(4-nitrophenylsul...)
Affinity DataIC50: 2.40E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040350(8-Amino-1,3-bis-cyclopropylmethyl-7-methanesulfony...)
Affinity DataIC50: 3.20E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040375(1,3-Bis(cyclopropylmethyl)-8-bis[(4-nitrophenylsul...)
Affinity DataIC50: 3.40E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040364(8-Amino-1,3-bis-cyclopropylmethyl-7-(3-trifluorome...)
Affinity DataIC50: 3.70E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040347(N-[1,3-Bis-cyclopropylmethyl-2,6-dioxo-7-(3,4,5-tr...)
Affinity DataIC50: 3.70E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040360(8-Amino-1,3-bis-cyclopropylmethyl-7-(4-nitro-benze...)
Affinity DataIC50: 3.80E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040344(8-Amino-1,3-bis-cyclopropylmethyl-7-(propane-2-sul...)
Affinity DataIC50: 3.80E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040367(8-Amino-1,3-bis-cyclopropylmethyl-7-(2,5-dimethoxy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040353(8-Amino-1,3-bis-cyclopropylmethyl-7-(4-trifluorome...)
Affinity DataIC50: 4.90E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040373(N-(1,3-Bis-cyclopropylmethyl-7-methyl-2,6-dioxo-2,...)
Affinity DataIC50: 5.30E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040378(N-(1,3-Bis-cyclopropylmethyl-7-methyl-2,6-dioxo-2,...)
Affinity DataIC50: 5.40E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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