Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50005622
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038923(1-[4-(2-Chloro-phenyl)-6,7-dimethyl-quinolin-3-yl]...)
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038906(1-[8-Chloro-4-(2-chloro-phenyl)-6-methyl-quinolin-...)
Affinity DataIC50: 8.90nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038918(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50: 9.20nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038900(1-(7-Chloro-6-methyl-4-o-tolyl-quinolin-3-yl)-3-(2...)
Affinity DataIC50: 9.30nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038920(1-[6-Chloro-4-(2-chloro-phenyl)-8-methyl-quinolin-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038922(1-(2,4-Difluoro-phenyl)-3-(6,8-dimethyl-4-o-tolyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038905(1-[4-(2-Chloro-phenyl)-6-isopropyl-quinolin-3-yl]-...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038919(1-[4-(2-Chloro-phenyl)-6-ethyl-quinolin-3-yl]-3-(2...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038915(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038912(1-[4-(2-Chloro-phenyl)-6-methyl-quinolin-3-yl]-3-(...)
Affinity DataIC50: 16.8nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038901(1-[6-Chloro-4-(2-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50: 21.2nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038907(1-(2,4-Difluoro-phenyl)-3-(6-methyl-4-o-tolyl-quin...)
Affinity DataIC50: 21.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038916(1-[6-Chloro-4-(2-methoxy-phenyl)-quinolin-3-yl]-3-...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038914(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038909(1-(6-Chloro-4-o-tolyl-quinolin-3-yl)-3-(2,4-difluo...)
Affinity DataIC50: 28.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038913(1-[6-Chloro-4-(3-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50: 90.6nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038917(1-[6-Chloro-4-(4-methoxy-phenyl)-quinolin-3-yl]-3-...)
Affinity DataIC50: 121nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038908(1-[4-(2-Chloro-phenyl)-quinolin-3-yl]-3-(2,4-diflu...)
Affinity DataIC50: 125nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038925(1-[4-(2-Chloro-phenyl)-5-methyl-quinolin-3-yl]-3-(...)
Affinity DataIC50: 149nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038910(1-(6-Chloro-4-p-tolyl-quinolin-3-yl)-3-(2,4-difluo...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038904(1-(6-Chloro-4-phenyl-quinolin-3-yl)-3-(2,4-difluor...)
Affinity DataIC50: 215nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038902(1-[6-Chloro-4-(4-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50: 534nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038911(1-(6-Chloro-4-phenyl-quinolin-3-yl)-3-(4-fluoro-ph...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038926(1-(6-Chloro-4-phenyl-quinolin-3-yl)-3-(2,4-dimetho...)
Affinity DataIC50: 864nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038927(1-(6-Chloro-4-phenyl-quinolin-3-yl)-3-(2-fluoro-ph...)
Affinity DataIC50: 929nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038903(1-(6-Chloro-4-phenyl-quinolin-3-yl)-3-phenyl-urea ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038921(3-(6-Chloro-4-phenyl-quinolin-3-yl)-1-(2,4-difluor...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038924(1-(4-Chloro-phenyl)-3-(6-chloro-4-phenyl-quinolin-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed