Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50005549
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]L-689,560 at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50: 400nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice release at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataEC50:  400nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]-GABA release at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038169(Cis-3-amino-1-hydroxy-4-methylpyrrolidin-2-one | 3...)
Affinity DataKi:  650nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038175((3R,4R)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...)
Affinity DataKi:  750nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009093(CHEMBL277411 | 6-Chloro-3-ethoxycarbonylmethyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for in vitro inhibition of oocytes at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001263(CHEMBL114610 | 5,7-Dichloro-4-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 2.10E+3nMAssay Description:Compound was evaluated for in vitro inhibition of spinal cord at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038159((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004952(CHEMBL31344 | 3-(2-Carboxy-ethyl)-4,6-dichloro-1H-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cGMP cerebellar slice at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009106(CHEMBL23255 | 3-Carboxymethyl-6-chloro-1H-indole-2...)
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was evaluated for in vitro inhibition of oocytes at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038157(6-Hydroxy-2,6-diaza-bicyclo[3.2.1]octan-7-one | CH...)
Affinity DataKi:  3.50E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030639(N-(6,7-Dichloro-3-oxo-3,4-dihydro-quinoxaline-2-ca...)
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038178((4R)-4-aminoisoxazolidin-3-one | cycloserine | (+)...)
Affinity DataEC50:  1.81E+4nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]TCP at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038160(1-aminocyclobutane carboxylic acid | 1-Amino-cyclo...)
Affinity DataIC50: 1.85E+4nMAssay Description:Compound was evaluated for in vitro inhibition of oocytes at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004938(CHEMBL300949 | 3-Carboxymethylsulfanyl-4,6-dichlor...)
Affinity DataEC50:  1.40E+5nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice at NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed