Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50036286
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataKi:  0.330nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25400(cid_657378 | CPA | CHEMBL68738 | (2R,3R,4S,5R)-2-[...)
Affinity DataKi:  0.590nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  0.600nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118812(CHEMBL119709 | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-io...)
Affinity DataKi:  1.10nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50106543(CHEMBL133566 | IAB-MECA | 5-[6-(4-Amino-3-iodo-ben...)
Affinity DataKi:  1.30nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088421((2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-p...)
Affinity DataKi:  1.40nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368540(CHEMBL609534)
Affinity DataKi:  2.10nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50407234(CHEMBL2113557)
Affinity DataKi:  2.30nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453443(CHEMBL2113562)
Affinity DataKi:  3.10nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50364060(CHEMBL1950647)
Affinity DataKi:  5.70nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50009525(2-CI Adenosine | 2-Chloroadenosine | CHEMBL285819 ...)
Affinity DataKi:  9.30nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088422((2R,3R,4S,5R)-2-(6-(3-iodobenzylamino)-9H-purin-9-...)
Affinity DataKi:  9.5nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453442(CHEMBL1256714)
Affinity DataKi:  14nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKi:  15nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368540(CHEMBL609534)
Affinity DataKi:  16nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50106543(CHEMBL133566 | IAB-MECA | 5-[6-(4-Amino-3-iodo-ben...)
Affinity DataKi:  18nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088422((2R,3R,4S,5R)-2-(6-(3-iodobenzylamino)-9H-purin-9-...)
Affinity DataKi:  18nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088421((2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-p...)
Affinity DataKi:  19nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088422((2R,3R,4S,5R)-2-(6-(3-iodobenzylamino)-9H-purin-9-...)
Affinity DataKi:  20nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088421((2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-p...)
Affinity DataKi:  39nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50364060(CHEMBL1950647)
Affinity DataKi:  50nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118812(CHEMBL119709 | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-io...)
Affinity DataKi:  54nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118812(CHEMBL119709 | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-io...)
Affinity DataKi:  56nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50009525(2-CI Adenosine | 2-Chloroadenosine | CHEMBL285819 ...)
Affinity DataKi:  63nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453444(CHEMBL2113561)
Affinity DataKi:  64nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453442(CHEMBL1256714)
Affinity DataKi:  116nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453444(CHEMBL2113561)
Affinity DataKi:  117nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453442(CHEMBL1256714)
Affinity DataKi:  172nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453444(CHEMBL2113561)
Affinity DataKi:  181nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50106543(CHEMBL133566 | IAB-MECA | 5-[6-(4-Amino-3-iodo-ben...)
Affinity DataKi:  197nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50241166(N6-benzylado | CHEMBL388757 | (2R,3R,4S,5R)-2-(6-(...)
Affinity DataKi:  203nMAssay Description:Inhibition of [3H]S-(4-Nitrobenzyl)-6-thioinosine binding to adenosine uptake sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  237nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25400(cid_657378 | CPA | CHEMBL68738 | (2R,3R,4S,5R)-2-[...)
Affinity DataKi:  240nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50364060(CHEMBL1950647)
Affinity DataKi:  400nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25400(cid_657378 | CPA | CHEMBL68738 | (2R,3R,4S,5R)-2-[...)
Affinity DataKi:  462nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataKi:  470nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKi:  584nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataKi:  820nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataKi:  950nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50009525(2-CI Adenosine | 2-Chloroadenosine | CHEMBL285819 ...)
Affinity DataKi:  1.89E+3nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50407234(CHEMBL2113557)
Affinity DataKi:  2.14E+3nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKi:  2.60E+3nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50407234(CHEMBL2113557)
Affinity DataKi:  3.21E+3nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453443(CHEMBL2113562)
Affinity DataKi:  4.12E+3nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453443(CHEMBL2113562)
Affinity DataKi:  4.89E+3nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataKi:  1.52E+4nMAssay Description:Inhibition of [3H]S-(4-Nitrobenzyl)-6-thioinosine binding to adenosine uptake sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118812(CHEMBL119709 | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-io...)
Affinity DataKi:  2.82E+4nMAssay Description:Inhibition of [3H]S-(4-Nitrobenzyl)-6-thioinosine binding to adenosine uptake sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50407234(CHEMBL2113557)
Affinity DataKi:  4.95E+4nMAssay Description:Inhibition of [3H]S-(4-Nitrobenzyl)-6-thioinosine binding to adenosine uptake sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed