Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50005499
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037669(1-[(R)-3-(4-Fluoro-phenyl)-cyclohex-3-enylmethyl]-...)
Affinity DataIC50: 76nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037671(1-[(R)-3-(4-Methoxy-phenyl)-cyclohex-3-enylmethyl]...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037670(4-Phenyl-1-(3-phenyl-cyclohex-3-enylmethyl)-1,2,3,...)
Affinity DataIC50: 112nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50453436(CHEMBL2111778)
Affinity DataIC50: 113nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037674(1-(3-Phenyl-cyclohex-3-enylmethyl)-4-pyridin-2-yl-...)
Affinity DataIC50: 141nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037668(1-(3-Phenyl-cyclohex-3-enylmethyl)-4-thiophen-2-yl...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037672(4-Phenyl-1-((R)-3-p-tolyl-cyclohex-3-enylmethyl)-1...)
Affinity DataIC50: 328nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037667(2-[4-(3-Phenyl-cyclohex-3-enylmethyl)-piperazin-1-...)
Affinity DataIC50: 354nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037673(4-Phenyl-1-(3-phenyl-cyclohex-2-enylmethyl)-1,2,3,...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037680(1-Phenyl-4-(3-phenyl-cyclohex-3-enylmethyl)-pipera...)
Affinity DataIC50: 424nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037679(4-Phenyl-1-[2-(3-phenyl-cyclohex-3-enyl)-ethyl]-1,...)
Affinity DataIC50: 635nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037681(4-Phenyl-1-(4-phenyl-cyclohex-3-enylmethyl)-1,2,3,...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037678(4-Phenyl-1-[(R)-3-(4-trifluoromethyl-phenyl)-cyclo...)
Affinity DataIC50: 2.55E+3nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037676(4-Phenyl-1-(2-phenyl-cyclohex-2-enylmethyl)-1,2,3,...)
Affinity DataIC50: 3.94E+3nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037675(1-[(R)-3-(4-Chloro-phenyl)-cyclohex-3-enylmethyl]-...)
Affinity DataIC50: 4.63E+3nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037677(4-Phenyl-1-(3-phenyl-cyclohex-3-enyl)-1,2,3,6-tetr...)
Affinity DataIC50: 9.21E+3nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.5nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.690nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.86nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi:  2.20nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  3.30nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi:  7.80nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  26nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi:  28nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  53nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  91nMAssay Description:Tested for binding affinity towards human Dopamine receptor D4.2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi: >221nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  467nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed