Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50005453
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037100(2,2-Dimethyl-propionic acid 3-{5-benzyloxycarbonyl...)
Affinity DataKi:  12nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037117(2,2-Dimethyl-propionic acid 4-{5-benzyloxycarbonyl...)
Affinity DataKi:  32nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037111({5-(4-Hydroxy-benzyl)-2-oxo-1-[(3,3,3-trifluoro-1-...)
Affinity DataKi:  34nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037102({2-Oxo-5-[3-(2,2,2-trifluoro-acetylamino)-benzyl]-...)
Affinity DataKi:  36nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037110({5-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  40nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037105(Acetic acid 3-{5-benzyloxycarbonylamino-6-oxo-1-[(...)
Affinity DataKi:  42nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037113([2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propy...)
Affinity DataKi:  47nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037116(N-{5-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-...)
Affinity DataKi:  48nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037098(N-{5-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-...)
Affinity DataKi:  51nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037118(N-{5-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-...)
Affinity DataKi:  70nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037099({5-(4-Fluoro-benzyl)-2-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  71nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037106({5-(3-Fluoro-benzyl)-2-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  87nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037107(4-{5-Benzyloxycarbonylamino-6-oxo-1-[(3,3,3-triflu...)
Affinity DataKi:  88nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037103({5-(3-Hydroxy-benzyl)-2-oxo-1-[(3,3,3-trifluoro-1-...)
Affinity DataKi:  89nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037109({2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propy...)
Affinity DataKi:  280nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037097(N-{2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-pro...)
Affinity DataKi:  320nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037108(N-{2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-pro...)
Affinity DataKi:  350nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037096(N-{2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-pro...)
Affinity DataKi:  500nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037101(N-{2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-pro...)
Affinity DataKi:  2.60E+3nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037112(2-(3-Amino-2-oxo-2H-pyridin-1-yl)-N-(3,3,3-trifluo...)
Affinity DataKi:  2.70E+3nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037115(2-(3-Acetylamino-2-oxo-2H-pyridin-1-yl)-N-(3,3,3-t...)
Affinity DataKi:  2.80E+3nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037114(N-{2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-pro...)
Affinity DataKi:  3.40E+3nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca

Curated by ChEMBL
LigandPNGBDBM50037104(2-(3-Nitro-2-oxo-2H-pyridin-1-yl)-N-(3,3,3-trifluo...)
Affinity DataKi:  1.50E+4nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed