Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50036386
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036134(32+/-82-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,1...)
Affinity DataKi:  0.000660nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DSLET (delta 2) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036134(32+/-82-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,1...)
Affinity DataKi:  0.00500nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036140(22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-ox...)
Affinity DataKi:  0.0130nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036138(5-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  0.0150nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DSLET (delta 2) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036140(22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-ox...)
Affinity DataKi:  0.0160nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DSLET (delta 2) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.0300nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036135(5-amino(imino)methylamino-2-[22-cyclopropylmethyl-...)
Affinity DataKi:  0.0830nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DSLET (delta 2) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036137(2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14...)
Affinity DataKi:  0.140nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036135(5-amino(imino)methylamino-2-[22-cyclopropylmethyl-...)
Affinity DataKi:  0.160nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036138(5-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  0.180nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036136(6-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  0.300nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036137(2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14...)
Affinity DataKi:  0.410nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DSLET (delta 2) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036136(6-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  0.75nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DSLET (delta 2) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  3.80nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036140(22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-ox...)
Affinity DataKi:  24nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036136(6-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  41nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036140(22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-ox...)
Affinity DataKi:  42nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036138(5-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  57nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036138(5-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  136nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036134(32+/-82-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,1...)
Affinity DataKi:  162nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036135(5-amino(imino)methylamino-2-[22-cyclopropylmethyl-...)
Affinity DataKi:  188nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036134(32+/-82-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,1...)
Affinity DataKi:  206nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036136(6-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S...)
Affinity DataKi:  219nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  332nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036135(5-amino(imino)methylamino-2-[22-cyclopropylmethyl-...)
Affinity DataKi:  333nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036137(2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14...)
Affinity DataKi:  368nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50036137(2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14...)
Affinity DataKi:  893nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed