Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50005237
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034690(3-{[(R)-1-((S)-6-Amino-2-tert-butoxycarbonylamino-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034703(3-{[1-(3-Piperidin-4-yl-propionyl)-piperidine-3-ca...)
Affinity DataIC50: 9nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034701(3-{[1-(6-Amino-hexanoyl)-piperidine-3-carbonyl]-am...)
Affinity DataIC50: 13nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034692(3-{[(S)-1-((S)-6-Amino-2-tert-butoxycarbonylamino-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034696((S)-2-{[1-((S)-6-Amino-2-tert-butoxycarbonylamino-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034700(3-{[1-((S)-6-Amino-2-tert-butoxycarbonylamino-hexa...)
Affinity DataIC50: 29nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034702(3-{[1-((R)-2-Acetylamino-6-amino-hexanoyl)-piperid...)
Affinity DataIC50: 74nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034694(3-{[1-((S)-2-Acetylamino-6-amino-hexanoyl)-piperid...)
Affinity DataIC50: 340nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034697(3-{[1-((R)-6-Amino-2-tert-butoxycarbonylamino-hexa...)
Affinity DataIC50: 740nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034685(3-{[1-((S)-2,6-Diamino-hexanoyl)-piperidine-3-carb...)
Affinity DataIC50: 760nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034704((S)-3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034689(3-{[1-((R)-2,6-Diamino-hexanoyl)-piperidine-3-carb...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034698(3-{[1-((R)-2-tert-Butoxycarbonylamino-5-guanidino-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034686(HisHisLeuGlyGlyAlaLysGlnAlaGlyAspVal | CHEMBL40943...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034691(3-{[1-(6-Amino-hexanoyl)-piperidin-3-ylmethyl]-ami...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034688(4-{[1-((S)-6-Amino-2-tert-butoxycarbonylamino-hexa...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034695(3-{[1-((R)-2-tert-Butoxycarbonylamino-6-isopropyla...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034684(3-{[(R)-1-((S)-6-Benzyloxycarbonylamino-2-tert-but...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034705({[1-((R)-2-Acetylamino-6-amino-hexanoyl)-piperidin...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034687([3-(2-tert-Butoxycarbonylamino-6-isopropylamino-he...)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of fibrinogen binding to isolated integrin alphaIIb-beta3 at 50 uM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034699({[1-((S)-6-Amino-2-tert-butoxycarbonylamino-hexano...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034693(4-{[1-((R)-6-Amino-2-tert-butoxycarbonylamino-hexa...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed