Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50036405
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 8.5nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM91713(Androst-4-en-3,17-dione, 2 | Androstenedione | And...)
Affinity DataIC50: 84nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034508((10R,13S,17S)-4-Hydroxy-10,13-dimethyl-3-oxo-2,3,6...)
Affinity DataIC50: 172nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034511((10R,13S,17S)-4-Chloro-10,13-dimethyl-3-oxo-2,3,6,...)
Affinity DataIC50: 192nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 218nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034509((10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7...)
Affinity DataIC50: 387nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034507((10R,13S,17S)-4-Mercapto-10,13-dimethyl-3-oxo-2,3,...)
Affinity DataIC50: 437nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034507((10R,13S,17S)-4-Mercapto-10,13-dimethyl-3-oxo-2,3,...)
Affinity DataIC50: 709nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034509((10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7...)
Affinity DataIC50: 981nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034508((10R,13S,17S)-4-Hydroxy-10,13-dimethyl-3-oxo-2,3,6...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034511((10R,13S,17S)-4-Chloro-10,13-dimethyl-3-oxo-2,3,6,...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM91713(Androst-4-en-3,17-dione, 2 | Androstenedione | And...)
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed