Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50005148
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033553(6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033547(6-[(2,6-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 9.90nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033555(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033557(6-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033550(6-{[(2,5-Diethoxy-phenyl)-methyl-amino]-methyl}-5,...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033556(6-{[(2,5-Dimethoxy-phenyl)-ethyl-amino]-methyl}-5,...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033546(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-5,...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033543(6-{[(4-Chloro-phenyl)-methyl-amino]-methyl}-5,6,7,...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033552(6-(2,3-Dihydro-indol-1-ylmethyl)-5,6,7,8-tetrahydr...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033540(6-[(3-Bromo-phenylamino)-methyl]-5,6,7,8-tetrahydr...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033546(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-5,...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033542(6-(Naphthalen-1-ylaminomethyl)-5,6,7,8-tetrahydro-...)
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033553(6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033539(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033543(6-{[(4-Chloro-phenyl)-methyl-amino]-methyl}-5,6,7,...)
Affinity DataIC50: 67nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033556(6-{[(2,5-Dimethoxy-phenyl)-ethyl-amino]-methyl}-5,...)
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033555(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)
Affinity DataIC50: 74nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033545(6-[(4-Chloro-phenylamino)-methyl]-5,6,7,8-tetrahyd...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033553(6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl...)
Affinity DataIC50: 95nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033554(6-[(2,5-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033547(6-[(2,6-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 109nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033556(6-{[(2,5-Dimethoxy-phenyl)-ethyl-amino]-methyl}-5,...)
Affinity DataIC50: 114nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033550(6-{[(2,5-Diethoxy-phenyl)-methyl-amino]-methyl}-5,...)
Affinity DataIC50: 116nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033555(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)
Affinity DataIC50: 119nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033545(6-[(4-Chloro-phenylamino)-methyl]-5,6,7,8-tetrahyd...)
Affinity DataIC50: 128nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033542(6-(Naphthalen-1-ylaminomethyl)-5,6,7,8-tetrahydro-...)
Affinity DataIC50: 139nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033548(6-[(2,5-Diethoxy-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033552(6-(2,3-Dihydro-indol-1-ylmethyl)-5,6,7,8-tetrahydr...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033543(6-{[(4-Chloro-phenyl)-methyl-amino]-methyl}-5,6,7,...)
Affinity DataIC50: 171nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033549(6-[(2,5-Dimethoxy-phenylamino)-methyl]-5,6,7,8-tet...)
Affinity DataIC50: 181nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033552(6-(2,3-Dihydro-indol-1-ylmethyl)-5,6,7,8-tetrahydr...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033540(6-[(3-Bromo-phenylamino)-methyl]-5,6,7,8-tetrahydr...)
Affinity DataIC50: 227nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033554(6-[(2,5-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033546(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-5,...)
Affinity DataIC50: 246nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033557(6-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033539(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033557(6-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033550(6-{[(2,5-Diethoxy-phenyl)-methyl-amino]-methyl}-5,...)
Affinity DataIC50: 319nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033538(6-{[Methyl-(3,4,5-trimethoxy-benzyl)-amino]-methyl...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033540(6-[(3-Bromo-phenylamino)-methyl]-5,6,7,8-tetrahydr...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033554(6-[(2,5-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033547(6-[(2,6-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 502nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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