Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50035498
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028603(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-prop-2-yny...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028604(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-octyl-amin...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028603(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-prop-2-yny...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of activity against Lactobacillus casei enzyme thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 7.50E+4nMAssay Description:In vitro inhibition of activity against Lactobacillus casei enzyme thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028604(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-octyl-amin...)
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibition of activity against Lactobacillus casei enzyme thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50028605(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-propyl-ami...)
Affinity DataKi:  0.00300nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataKi:  0.00400nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00600nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50028603(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-prop-2-yny...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50028604(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-octyl-amin...)
Affinity DataKi:  18nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed