Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50034923
TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291559({2-Benzo[1,3]dioxol-5-yl-1-[(S)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291555({2-Benzo[1,3]dioxol-4-yl-1-[(S)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291558({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50064106({[(S)-2-Biphenyl-4-yl-1-(2H-tetrazol-5-yl)-ethylam...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291557({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291556({2-Benzo[1,3]dioxol-5-yl-1-[(R)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291561({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50159369({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291562({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291564({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291561({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291557({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 30nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50159369({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291559({2-Benzo[1,3]dioxol-5-yl-1-[(S)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 93nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291555({2-Benzo[1,3]dioxol-4-yl-1-[(S)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291562({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291558({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291556({2-Benzo[1,3]dioxol-5-yl-1-[(R)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 390nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50064106({[(S)-2-Biphenyl-4-yl-1-(2H-tetrazol-5-yl)-ethylam...)
Affinity DataIC50: 410nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291560({[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291553({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291565({[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291554({2-Benzo[1,3]dioxol-4-yl-1-[(R)-2-biphenyl-4-yl-1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291563({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291564({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article