Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50034717
TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataIC50: 77nMAssay Description:Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280447((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataIC50: 85nMAssay Description:Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280448(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataIC50: 85nMAssay Description:Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280448(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280447((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataIC50: 155nMAssay Description:Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280446(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280446(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280448(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280447((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280448(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataKi:  1.80nMAssay Description:Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280447((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataKi:  3.20nMAssay Description:Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280446(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280446(2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50214705(9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...)
Affinity DataKi:  18nMAssay Description:Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50005795(CHEMBL285627 | PD-119229-2 | 2,8-Diamino-9-thiophe...)
Affinity DataKi:  67nMAssay Description:Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPurine nucleoside phosphorylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50005799(CHEMBL8230 | 2,8-Diamino-9-benzyl-1,9-dihydro-puri...)
Affinity DataKi:  200nMAssay Description:Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article