Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50030133
TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291446((R)-2-(2-Mercapto-acetylamino)-N-((S)-1-methylcarb...)
Affinity DataIC50: 6nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291447((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 7nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 (MMP-9) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291447((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 12nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291446((R)-2-(2-Mercapto-acetylamino)-N-((S)-1-methylcarb...)
Affinity DataIC50: 13nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291444((R)-N-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-eth...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291445((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 30nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 (MMP-9) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290672((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 50nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291445((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290672((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 90nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291444((R)-N-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-eth...)
Affinity DataIC50: 120nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 (MMP-9) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291443((R)-2-(2-Mercapto-acetylamino)-3-methanesulfinyl-N...)
Affinity DataIC50: 350nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291447((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 430nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291445((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 430nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291443((R)-2-(2-Mercapto-acetylamino)-3-methanesulfinyl-N...)
Affinity DataIC50: 480nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291446((R)-2-(2-Mercapto-acetylamino)-N-((S)-1-methylcarb...)
Affinity DataIC50: 650nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291444((R)-N-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-eth...)
Affinity DataIC50: 810nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291441((S)-3-Hydroxy-2-(2-mercapto-acetylamino)-N-((S)-1-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290672((S)-2-(2-Mercapto-acetylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 2.60E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291449((S)-4-Methyl-2-(2-methylsulfanyl-acetylamino)-pent...)
Affinity DataIC50: 2.60E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291441((S)-3-Hydroxy-2-(2-mercapto-acetylamino)-N-((S)-1-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291449((S)-4-Methyl-2-(2-methylsulfanyl-acetylamino)-pent...)
Affinity DataIC50: 4.60E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291448((S)-2-(3-Mercapto-propionylamino)-4-methyl-pentano...)
Affinity DataIC50: 5.10E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291443((R)-2-(2-Mercapto-acetylamino)-3-methanesulfinyl-N...)
Affinity DataIC50: 8.50E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291448((S)-2-(3-Mercapto-propionylamino)-4-methyl-pentano...)
Affinity DataIC50: 9.60E+3nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291442((S)-4-Methyl-2-propionylamino-pentanoic acid ((S)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-9 in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291449((S)-4-Methyl-2-(2-methylsulfanyl-acetylamino)-pent...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291448((S)-2-(3-Mercapto-propionylamino)-4-methyl-pentano...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291442((S)-4-Methyl-2-propionylamino-pentanoic acid ((S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291441((S)-3-Hydroxy-2-(2-mercapto-acetylamino)-N-((S)-1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-3 (MMP-3) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetNeutrophil collagenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291442((S)-4-Methyl-2-propionylamino-pentanoic acid ((S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Matrix metalloprotease-8 (MMP-8) in adjuvant arthritic rat model of rheumatoid arthritisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article