Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50030088
TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291004(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50: 315nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 791nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50: 923nMAssay Description:In vitro inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291005(5-Oxo-6-phenylmethanesulfonylamino-hexahydro-thiaz...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article