Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50030086
TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290988(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataIC50: 300nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290988(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataIC50: 500nMAssay Description:Compound concentration that cause 50% inhibition of pig liver oxidosqualene cyclase (OSC) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290991(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290992(3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290989(3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...)
Affinity DataIC50: 1.80E+4nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290987(3-(18,18-Difluoro-3,7,12-trimethyl-octadeca-3,7,11...)
Affinity DataIC50: 6.00E+4nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290990(2,2-Dimethyl-3-(3,7,12-trimethyl-octadeca-3,7,11,1...)
Affinity DataIC50: 6.00E+4nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290988(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290991(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataKi:  4.50E+3nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290992(3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...)
Affinity DataKi:  1.02E+4nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetLanosterol synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290989(3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...)
Affinity DataKi:  1.20E+4nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article