Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50029924
TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM25756(Betalok | Spesikor | {2-hydroxy-3-[4-(2-methoxyeth...)
Affinity DataIC50: 190nMAssay Description:Tested for beta-1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM25756(Betalok | Spesikor | {2-hydroxy-3-[4-(2-methoxyeth...)
Affinity DataIC50: 320nMAssay Description:Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM25756(Betalok | Spesikor | {2-hydroxy-3-[4-(2-methoxyeth...)
Affinity DataIC50: 500nMAssay Description:The compound was tested for its ability to inhibit (-)-[3H]dihydroalprenolol binding to beta-adrenergic receptor sites in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50289372((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...)
Affinity DataIC50: 1.35E+3nMAssay Description:Tested for beta-1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289372((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...)
Affinity DataIC50: 1.54E+3nMAssay Description:The compound was tested for its ability to inhibit (-)-[3H]dihydroalprenolol binding to beta-adrenergic receptor sites in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50289372((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...)
Affinity DataIC50: 2.15E+3nMAssay Description:Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50214285(CHEMBL279012)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for its ability to inhibit (-)-[3H]dihydroalprenolol binding to beta-adrenergic receptor sites in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article