Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50029852
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288686(Phosphinic acid derivative | CHEMBL110312)
Affinity DataIC50: 50nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288686(Phosphinic acid derivative | CHEMBL110312)
Affinity DataIC50: 260nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288692([(S)-2-((S)-1-Benzylcarbamoyl-3-methyl-butylcarbam...)
Affinity DataIC50: 430nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288688(Phosphinic acid derivative | CHEMBL419395)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288692([(S)-2-((S)-1-Benzylcarbamoyl-3-methyl-butylcarbam...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288688(Phosphinic acid derivative | CHEMBL419395)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288689([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-ph...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of collagenase-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288689([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-ph...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of stromelysin-1 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288674([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288673({4-[((S)-1-Benzoyl-pyrrolidine-2-carbonyl)-amino]-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288672([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288683([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288672([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288677([(E)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-but-2...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288677([(E)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-but-2...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288678([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288681((4-Benzoylamino-butyl)-[(S)-2-((S)-3-methyl-1-phen...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288687({4-[((S)-1-Acetyl-pyrrolidine-2-carbonyl)-amino]-b...)
Affinity DataKi:  6.10nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288678([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288683([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  12nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288673({4-[((S)-1-Benzoyl-pyrrolidine-2-carbonyl)-amino]-...)
Affinity DataKi:  13nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288699((4-Ethoxycarbonylamino-butyl)-[(S)-2-((S)-3-methyl...)
Affinity DataKi:  16nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288668([4-(3-Ethyl-ureido)-butyl]-[(S)-2-((S)-3-methyl-1-...)
Affinity DataKi:  17nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288668([4-(3-Ethyl-ureido)-butyl]-[(S)-2-((S)-3-methyl-1-...)
Affinity DataKi:  19nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288674([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  20nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288682({4-[((R)-1-Benzoyl-pyrrolidine-2-carbonyl)-amino]-...)
Affinity DataKi:  24nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288675({4-[((R)-1-Acetyl-pyrrolidine-2-carbonyl)-amino]-b...)
Affinity DataKi:  26nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288681((4-Benzoylamino-butyl)-[(S)-2-((S)-3-methyl-1-phen...)
Affinity DataKi:  26nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288679([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  30nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288684([4-(3-Benzyl-ureido)-butyl]-[(S)-2-((S)-3-methyl-1...)
Affinity DataKi:  50nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288693((4-Methoxycarbonylamino-butyl)-[(S)-2-((S)-3-methy...)
Affinity DataKi:  54nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288694([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  56nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288687({4-[((S)-1-Acetyl-pyrrolidine-2-carbonyl)-amino]-b...)
Affinity DataKi:  62nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288695((4-Benzyloxycarbonylamino-butyl)-[(S)-2-((S)-3-met...)
Affinity DataKi:  63nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288685([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  70nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288679([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  130nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288690([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  130nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288669([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  170nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288698({[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-acetylam...)
Affinity DataKi:  410nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288691([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  440nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288696([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  470nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288676(3-{Hydroxy-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-...)
Affinity DataKi:  520nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288697((2-Benzylcarbamoyl-ethyl)-[(S)-2-((S)-3-methyl-1-p...)
Affinity DataKi:  540nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288680(Methyl-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-buty...)
Affinity DataKi:  570nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288671([(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbam...)
Affinity DataKi:  670nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288676(3-{Hydroxy-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288680(Methyl-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-buty...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288670((4-Amino-butyl)-[(S)-2-((S)-3-methyl-1-phenylcarba...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288691([4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article