Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50029811
TargetMetabotropic glutamate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataEC50:  2.10E+5nMAssay Description:Compound was tested for its agonist activity against mGluR1a receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataEC50: >6.00E+5nMAssay Description:Compound was tested for its agonist activity against mGluR 2 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataEC50:  1.05E+5nMAssay Description:Compound was tested for its agonist activity against mGluR 5a receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 700nMAssay Description:Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor kainate using [3H]kainate as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested in vitro for binding affinity against mGluR1a metabotropic glutamate receptor, using [3H]glutamate as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for its agonist activity against mGluR 6 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for its antagonist activity against mGluR 6 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 3.15E+5nMAssay Description:Compound was tested in vitro for binding affinity against mGluR4a metabotropic glutamate receptor, using [3H]L-AP4 as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 6.00E+5nMAssay Description:Compound was tested for its antagonist activity against mGluR 2 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate receptor 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: 6.60E+5nMAssay Description:Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor AMPA, using [3H]TCP as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article