Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50029802
TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024096(((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  1.70nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  2.20nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataKi:  4.70nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288076(((E)-2-Mercaptomethyl-3-phenyl-acryloylamino)-acet...)
Affinity DataKi:  4.90nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288074((2-Benzyl-2-mercaptomethyl-3-phenyl-propionylamino...)
Affinity DataKi: >100nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288077([(2-Mercaptomethyl-indane-2-carbonyl)-amino]-aceti...)
Affinity DataKi:  162nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288076(((E)-2-Mercaptomethyl-3-phenyl-acryloylamino)-acet...)
Affinity DataKi:  380nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288075(((Z)-2-Mercaptomethyl-3-phenyl-acryloylamino)-acet...)
Affinity DataKi:  408nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article