Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50029733
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(RS-39066 | 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-...)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(RS-39066 | 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 1nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287383((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 1nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287378((R)-N*1*-[(S)-1-(1H-Benzoimidazol-2-yl)-3-methyl-b...)
Affinity DataIC50: 2nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287381((S)-2-Cyclohexyl-N*4*-hydroxy-N*1*-[(S)-3-methyl-1...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287380((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(6-methoxy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(RS-39066 | 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287378((R)-N*1*-[(S)-1-(1H-Benzoimidazol-2-yl)-3-methyl-b...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287385((R)-N*1*-[1-(1H-Benzoimidazol-2-yl)-2-(1H-indol-3-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287380((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(6-methoxy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287386((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-2-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287386((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-2-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287385((R)-N*1*-[1-(1H-Benzoimidazol-2-yl)-2-(1H-indol-3-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287385((R)-N*1*-[1-(1H-Benzoimidazol-2-yl)-2-(1H-indol-3-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287378((R)-N*1*-[(S)-1-(1H-Benzoimidazol-2-yl)-3-methyl-b...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287380((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(6-methoxy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 33nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287382(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 70nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287383((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 112nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287383((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287386((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-2-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287382(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287381((S)-2-Cyclohexyl-N*4*-hydroxy-N*1*-[(S)-3-methyl-1...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287382(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287381((S)-2-Cyclohexyl-N*4*-hydroxy-N*1*-[(S)-3-methyl-1...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article