Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50029731
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287337(N-[2-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-N-met...)
Affinity DataIC50: 10nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287354(N-[2-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-N-met...)
Affinity DataIC50: 14nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287355(N-(3,5-Dichloro-benzyl)-N-methyl-3,3-diphenyl-prop...)
Affinity DataIC50: 45nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287345(N-[2-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-2,2-d...)
Affinity DataIC50: 46nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287349(N-(3,5-Bis-trifluoromethyl-benzyl)-N-methyl-2,2-di...)
Affinity DataIC50: 47nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287340(N-(3,5-Bis-trifluoromethyl-benzyl)-N-methyl-3,3-di...)
Affinity DataIC50: 56nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287358(N-[2-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-3,3-d...)
Affinity DataIC50: 112nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287341(2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl...)
Affinity DataIC50: 114nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287351(N-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-3,3-di...)
Affinity DataIC50: 121nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287347(N-(3,5-Dichloro-benzyl)-3,3-diphenyl-propionamide ...)
Affinity DataIC50: 226nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287352(N-(3,5-Dimethoxy-benzyl)-N-methyl-3,3-diphenyl-pro...)
Affinity DataIC50: 226nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287348(N-(3,5-Bis-trifluoromethyl-benzyl)-3,3-diphenyl-pr...)
Affinity DataIC50: 235nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287357(N-(2,2-Diphenyl-ethyl)-N-methyl-3,5-bis-trifluorom...)
Affinity DataIC50: 297nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287356(N-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-2,2-di...)
Affinity DataIC50: 301nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287350(N-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-N-me...)
Affinity DataIC50: 304nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287335(N-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-N-me...)
Affinity DataIC50: 323nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287343(2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl...)
Affinity DataIC50: 378nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287336(N-(3,5-Bis-trifluoromethyl-benzyl)-2,2-diphenyl-ac...)
Affinity DataIC50: 526nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287342(N-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-2,2-...)
Affinity DataIC50: 593nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287353(N-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-3,3-...)
Affinity DataIC50: 620nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287338(N-(3,5-Dimethoxy-benzyl)-3,3-diphenyl-propionamide...)
Affinity DataIC50: 2.24E+3nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287339(N-(3,5-Bis-trifluoromethyl-phenyl)-3,3-diphenyl-pr...)
Affinity DataIC50: 3.01E+3nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287344(N-(2,2-Diphenyl-ethyl)-3,5-bis-trifluoromethyl-ben...)
Affinity DataIC50: 3.92E+3nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287346(N-(3,5-Bis-trifluoromethyl-phenyl)-2,2-diphenyl-ac...)
Affinity DataIC50: 6.56E+3nMAssay Description:Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article