Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50029633
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi: <1nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataKi: <1nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286354((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi: <2nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataKi:  2nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi: <2nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286354((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataKi: <2nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi: <2nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031770((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286352((R)-2-(4-Benzyloxy-butyl)-N*1*-((S)-2,2-dimethyl-1...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi:  6nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  8nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286352((R)-2-(4-Benzyloxy-butyl)-N*1*-((S)-2,2-dimethyl-1...)
Affinity DataKi:  11nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286354((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataKi:  11nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  14nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031770((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataKi:  14nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi:  15nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286355((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...)
Affinity DataKi:  20nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  26nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  28nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286352((R)-2-(4-Benzyloxy-butyl)-N*1*-((S)-2,2-dimethyl-1...)
Affinity DataKi:  39nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataKi:  46nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi:  89nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286351((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-methyl...)
Affinity DataKi: >100nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286355((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...)
Affinity DataKi:  100nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286351((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-methyl...)
Affinity DataKi:  170nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286355((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...)
Affinity DataKi:  180nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataKi:  190nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataKi:  300nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataKi:  330nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286353((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  500nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286352((R)-2-(4-Benzyloxy-butyl)-N*1*-((S)-2,2-dimethyl-1...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031770((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286355((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286351((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-methyl...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286353((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286351((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-methyl...)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286354((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286353((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286353((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article