Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50029632
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031783((R)-2-(3-Benzyloxy-propyl)-N*4*-hydroxy-N*1*-((S)-...)
Affinity DataKi: <1nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031772((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  2nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi: <2nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi: <2nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi:  2nMAssay Description:Inhibitory concentration of compound against human fibroblast stromelysin (HFS) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031788((R)-N4-hydroxy-2-(5-hydroxypentyl)-N1-((S)-1-(meth...)
Affinity DataKi:  4nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  6nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi:  7nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031785((R)-N4-hydroxy-2-(4-hydroxybutyl)-N1-((S)-1-(methy...)
Affinity DataKi:  7nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  8nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  14nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi:  15nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi:  20nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  26nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi:  28nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  30nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031788((R)-N4-hydroxy-2-(5-hydroxypentyl)-N1-((S)-1-(meth...)
Affinity DataKi:  31nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  32nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031783((R)-2-(3-Benzyloxy-propyl)-N*4*-hydroxy-N*1*-((S)-...)
Affinity DataKi:  43nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031785((R)-N4-hydroxy-2-(4-hydroxybutyl)-N1-((S)-1-(methy...)
Affinity DataKi:  64nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataKi:  79nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  92nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031784((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031783((R)-2-(3-Benzyloxy-propyl)-N*4*-hydroxy-N*1*-((S)-...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phe...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031793((R)-6-Hydroxycarbamoyl-5-((S)-1-methylcarbamoyl-2-...)
Affinity DataKi:  270nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031772((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  360nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031788((R)-N4-hydroxy-2-(5-hydroxypentyl)-N1-((S)-1-(meth...)
Affinity DataKi:  430nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031771((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031778((R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-((S)-1...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031785((R)-N4-hydroxy-2-(4-hydroxybutyl)-N1-((S)-1-(methy...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031783((R)-2-(3-Benzyloxy-propyl)-N*4*-hydroxy-N*1*-((S)-...)
Affinity DataKi:  2.27E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031793((R)-6-Hydroxycarbamoyl-5-((S)-1-methylcarbamoyl-2-...)
Affinity DataKi:  3.35E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031772((R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50031793((R)-6-Hydroxycarbamoyl-5-((S)-1-methylcarbamoyl-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article