Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50029525
TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036133(7-ethyl-7-hydroxy-(7S)-7,8,11,13-tetrahydro-10H-[1...)
Affinity DataIC50: 30nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285229(7-ethyl-7-hydroxy-(7S)-7,8,11,13-tetrahydro-10H-[1...)
Affinity DataIC50: 150nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285230((S)-9-Amino-4-ethyl-4,8-dihydroxy-1,12-dihydro-4H-...)
Affinity DataIC50: 170nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 700nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article