Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50029436
TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50117909(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284470(Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imi...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50117909(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284468(5-Isobutyl-thiophene-2-sulfonic acid {2-benzo[1,3]...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284468(5-Isobutyl-thiophene-2-sulfonic acid {2-benzo[1,3]...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284470(Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imi...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284472(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284466(5-Isobutyl-3H-1lambda*4*-thiophene-2-sulfonic acid...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284469(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284474(3H-1lambda*4*-Thiophene-2-sulfonic acid {2-benzo[1...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284466(5-Isobutyl-3H-1lambda*4*-thiophene-2-sulfonic acid...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284467(Propane-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284473(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284474(3H-1lambda*4*-Thiophene-2-sulfonic acid {2-benzo[1...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284471(Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imi...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284469(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284472(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284471(Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imi...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284473(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284467(Propane-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284444([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175515((2,5-Dibromo-3,4-dimethoxy-phenyl)-[4-(2-ethyl-5,7...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175515((2,5-Dibromo-3,4-dimethoxy-phenyl)-[4-(2-ethyl-5,7...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284444([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article