Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50029381
LigandPNGBDBM50042493(N-hydroxy-N-[(6-phenoxy-2H-chromen-3-yl)methyl]ure...)
Affinity DataIC50: 37nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50042493(N-hydroxy-N-[(6-phenoxy-2H-chromen-3-yl)methyl]ure...)
Affinity DataIC50: 40nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283975(N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 89nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283975(N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 91nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283977(N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 91nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283977(N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 98nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283976(N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 100nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283974(N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzothiepin...)
Affinity DataIC50: 120nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283974(N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzothiepin...)
Affinity DataIC50: 130nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283976(N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 130nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283973(N-hydroxy-N-[(8-phenoxy-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 180nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283973(N-hydroxy-N-[(8-phenoxy-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 210nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article