Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50029300
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154580(1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethy...)
Affinity DataIC50: 9.30nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283090((S)-2-(3,5-Dimethyl-benzyloxy)-1-phenyl-ethylamine...)
Affinity DataIC50: 55nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283087(1-(5H-Dibenzo[a,d]cyclohepten-5-yl)-2-(3,5-dimethy...)
Affinity DataIC50: 80nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283084(1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-...)
Affinity DataIC50: 93nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283088(1-(3,5-Dimethyl-benzyloxymethyl)-2-phenyl-ethylami...)
Affinity DataIC50: 483nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283086(1-(3,5-Dimethyl-benzyloxymethyl)-2-naphthalen-1-yl...)
Affinity DataIC50: 1.16E+3nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283085(1-(3,5-Dimethyl-benzyloxymethyl)-2-naphthalen-2-yl...)
Affinity DataIC50: 2.33E+3nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283091(1-(3,5-Dimethyl-benzyloxymethyl)-2-(1H-indol-3-yl)...)
Affinity DataIC50: 2.33E+3nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283089((R)-2-(3,5-Dimethyl-benzyloxy)-1-phenyl-ethylamine...)
Affinity DataIC50: 2.50E+3nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article