Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50029252
Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataEC50:  110nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056396(4-Amino-5-chloro-2-methoxy-benzoic acid (S)-(1-aza...)
Affinity DataEC50:  153nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056399(4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza...)
Affinity DataEC50:  110nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282690(4-Amino-5-chloro-2-methoxy-benzoic acid 1-ethyl-pi...)
Affinity DataEC50:  44nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataEC50:  260nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(SDZ-205557 | SDZ 205557 | 2-diethylaminoethyl [2-m...)
Affinity DataEC50: >1.00E+3nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282688(4-Amino-5-chloro-2-methoxy-benzoic acid 1-ethyl-pi...)
Affinity DataEC50:  22nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  5nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM29526(CHEMBL286136 | 2-Piperidinoethyl 4-amino-5-chloro-...)
Affinity DataEC50:  4nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataEC50:  27nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM29526(CHEMBL286136 | 2-Piperidinoethyl 4-amino-5-chloro-...)
Affinity DataIC50: 2.40nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity was determined by the relaxation of the carbachol-contracted rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 3.70nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity was determined by the relaxation of the carbachol-contracted rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056399(4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza...)
Affinity DataIC50: 30nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity expressed as the concentration which produced a 50% reduction of 5-HT induced contraction in guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataIC50: 60nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity expressed as the concentration which produced a 50% reduction of 5-HT induced contraction in guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(SDZ-205557 | SDZ 205557 | 2-diethylaminoethyl [2-m...)
Affinity DataIC50: 77nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity expressed as the concentration which produced a 50% reduction of 5-HT induced contraction in guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50056396(4-Amino-5-chloro-2-methoxy-benzoic acid (S)-(1-aza...)
Affinity DataIC50: 450nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity expressed as the concentration which produced a 50% reduction of 5-HT induced contraction in guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50056396(4-Amino-5-chloro-2-methoxy-benzoic acid (S)-(1-aza...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM29526(CHEMBL286136 | 2-Piperidinoethyl 4-amino-5-chloro-...)
Affinity DataKi:  1.07nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50056399(4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50056401(SDZ-205557 | SDZ 205557 | 2-diethylaminoethyl [2-m...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282688(4-Amino-5-chloro-2-methoxy-benzoic acid 1-ethyl-pi...)
Affinity DataKi:  10.3nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataKi:  23nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282690(4-Amino-5-chloro-2-methoxy-benzoic acid 1-ethyl-pi...)
Affinity DataKi:  34.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataKi:  64.3nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataKi:  72nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50056396(4-Amino-5-chloro-2-methoxy-benzoic acid (S)-(1-aza...)
Affinity DataKi:  91nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50282688(4-Amino-5-chloro-2-methoxy-benzoic acid 1-ethyl-pi...)
Affinity DataKi:  118nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50056401(SDZ-205557 | SDZ 205557 | 2-diethylaminoethyl [2-m...)
Affinity DataKi:  205nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  443nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50056399(4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza...)
Affinity DataKi:  488nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  753nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM29526(CHEMBL286136 | 2-Piperidinoethyl 4-amino-5-chloro-...)
Affinity DataKi:  782nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  975nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article