Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50029194
TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50013027(CHEMBL262655 | Sodium; 3-[4-(4-chloro-benzenesulfo...)
Affinity DataIC50: 0.900nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282138(Sodium; 3-[4-(4-chloro-phenylsulfamoyl)-butyl]-6-i...)
Affinity DataIC50: 220nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282135(Sodium; 3-[3-(4-chloro-phenylsulfamoyl)-propyl]-6-...)
Affinity DataIC50: 860nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282141(Sodium; 3-[5-(4-chloro-phenylsulfamoyl)-pentyl]-6-...)
Affinity DataIC50: 860nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282152(Sodium; 6-isopropyl-3-(5-phenylsulfamoyl-pentyl)-a...)
Affinity DataIC50: 1.40E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282136(6-Isopropyl-3-(5-phenylsulfamoyl-pentyl)-azulene-1...)
Affinity DataIC50: 1.50E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | CHEMBL8273 | [4-(2-Benzenesulfonylamino...)
Affinity DataIC50: 1.50E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282146(Sodium; 6-isopropyl-3-(4-phenylsulfamoyl-butyl)-az...)
Affinity DataIC50: 1.50E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282156(3-[5-(4-Chloro-phenylsulfamoyl)-pentyl]-6-isopropy...)
Affinity DataIC50: 1.70E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282139(3-[4-(4-Chloro-phenylsulfamoyl)-butyl]-6-isopropyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282133(Sodium; 6-isopropyl-3-(3-phenylsulfamoyl-propyl)-a...)
Affinity DataIC50: 8.70E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282154(6-Isopropyl-3-(4-phenylsulfamoyl-butyl)-azulene-1-...)
Affinity DataIC50: 8.70E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282147(3-[3-(4-Chloro-phenylsulfamoyl)-propyl]-6-isopropy...)
Affinity DataIC50: 9.10E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282134(6-Isopropyl-3-(3-phenylsulfamoyl-propyl)-azulene-1...)
Affinity DataIC50: 1.20E+4nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282144(3-[4-(4-Chloro-benzenesulfonylamino)-4-oxo-butyl]-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282148(Sodium; 3-[4-(4-chloro-benzenesulfonylamino)-4-oxo...)
Affinity DataIC50: 5.40E+4nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282140(Sodium; 3-(4-benzenesulfonylamino-4-oxo-butyl)-6-i...)
Affinity DataIC50: 6.50E+4nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282137(3-{[2-(4-Chloro-benzenesulfonylamino)-acetylamino]...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282155(3-(4-Benzenesulfonylamino-4-oxo-butyl)-6-isopropyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282151(Semicarbazone Derivative | CHEMBL297315)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282150(Thiosemicarbazone Derivative | CHEMBL296652)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282149(3-[(2-Benzenesulfonylamino-acetylamino)-methyl]-6-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282142(3-[(2-Benzoylamino-acetylamino)-methyl]-6-isopropy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (TXA2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282145(Semicarbazone Derivative | CHEMBL296727)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282143(3-{[2-(4-Chloro-benzoylamino)-acetylamino]-methyl}...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282153(Thiosemicarbazone Derivative | CHEMBL47635)
Affinity DataIC50: 5.90E+5nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article