Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50028993
LigandPNGBDBM50003351(CHEMBL101054 | 5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50003351(CHEMBL101054 | 5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50006579(CHEMBL75907 | 5-(4-Butoxy-furazan-3-yl)-1-methyl-1...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50003371(CHEMBL74786 | 5-(4-Hexyloxy-furazan-3-yl)-1-methyl...)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM46858(cid_9301 | ARECOLINE HYDROBROMIDE | SMR000058258 |...)
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50003371(CHEMBL74786 | 5-(4-Hexyloxy-furazan-3-yl)-1-methyl...)
Affinity DataIC50: 277nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006579(CHEMBL75907 | 5-(4-Butoxy-furazan-3-yl)-1-methyl-1...)
Affinity DataIC50: 345nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006584(McN-A-343 | (McN-A-343) [4-(3-Chloro-phenylcarbamo...)
Affinity DataIC50: 355nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280531(5-(4-Butoxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetrah...)
Affinity DataIC50: 369nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280531(5-(4-Butoxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetrah...)
Affinity DataIC50: 477nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280532(5-(3-Butoxy-isothiazol-4-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50: 544nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280532(5-(3-Butoxy-isothiazol-4-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50: 565nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280533(5-(4-Hexyloxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50: 663nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280530(5-(3-Hexyloxy-isothiazol-4-yl)-1-methyl-1,2,3,6-te...)
Affinity DataIC50: 715nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212579(CHEMBL167375)
Affinity DataIC50: 759nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280530(5-(3-Hexyloxy-isothiazol-4-yl)-1-methyl-1,2,3,6-te...)
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280533(5-(4-Hexyloxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006584(McN-A-343 | (McN-A-343) [4-(3-Chloro-phenylcarbamo...)
Affinity DataIC50: 955nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM46858(cid_9301 | ARECOLINE HYDROBROMIDE | SMR000058258 |...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article