Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50028992
LigandPNGBDBM50004665(1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50: 21nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50: 22nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50: 59nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006584(McN-A-343 | (McN-A-343) [4-(3-Chloro-phenylcarbamo...)
Affinity DataIC50: 64nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50: 68nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212575(CHEMBL165985)
Affinity DataIC50: 101nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212577(CHEMBL168032)
Affinity DataIC50: 139nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212578(CHEMBL167419)
Affinity DataIC50: 214nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004665(1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...)
Affinity DataIC50: 364nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212576(CHEMBL167689)
Affinity DataIC50: 373nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004665(1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...)
Affinity DataIC50: 407nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004665(1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...)
Affinity DataIC50: 858nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50: 920nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212576(CHEMBL167689)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50: 2.01E+3nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50: 2.45E+3nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50: 4.46E+3nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006584(McN-A-343 | (McN-A-343) [4-(3-Chloro-phenylcarbamo...)
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50: 6.50E+3nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006584(McN-A-343 | (McN-A-343) [4-(3-Chloro-phenylcarbamo...)
Affinity DataIC50: 7.24E+3nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212578(CHEMBL167419)
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50: 1.89E+4nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50: 2.59E+4nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50006584(McN-A-343 | (McN-A-343) [4-(3-Chloro-phenylcarbamo...)
Affinity DataIC50: 3.41E+4nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50: 3.42E+4nMAssay Description:Displacement of [3H]QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212577(CHEMBL168032)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50: 5.18E+4nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50212575(CHEMBL165985)
Affinity DataIC50: 5.54E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50: 8.79E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50: 8.79E+4nMAssay Description:Displacement of [3H]QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article