Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50028914
TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280119(2-[2-(1H-Imidazol-4-yl)-ethyl]-1-methyl-isothioure...)
Affinity DataEC50:  15nMAssay Description:The compound was evaluated for agonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280120((R)-2-(1H-Imidazol-4-yl)-propylamine; hydrobromide...)
Affinity DataEC50:  4nMAssay Description:Compound was evaluated for agonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)
Affinity DataEC50:  1nMAssay Description:The compound was evaluated for agonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM7966([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...)
Affinity DataEC50:  62nMAssay Description:Compound was evaluated for antagonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280118(2-[2-(1H-Imidazol-4-yl)-ethyl]-1,3-dimethyl-isothi...)
Affinity DataKi:  51nMAssay Description:The compound was evaluated for antagonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280117(4-[2-(4,5-Dihydro-1H-imidazol-2-ylsulfanyl)-ethyl]...)
Affinity DataKi:  260nMAssay Description:The compound was evaluated for antagonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetHistamine H3 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280121(2-[2-(1H-Imidazol-4-yl)-ethyl]-1,1-dimethyl-isothi...)
Affinity DataKi:  500nMAssay Description:The compound was evaluated for antagonistic effect on release of [3H]histamine from rat brain cortical slices with L-[3H]histidine at 0.3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article