Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 310
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM318((2R,3R)-2-(propan-2-yl)thiolan-3-yl N-[(2S,3R)-4-[...)
Affinity DataIC50: 0.260nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285971([(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6-tert-butylcarb...)
Affinity DataIC50: 0.260nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM306((2S,3S)-2-methyloxolan-3-yl N-[(2R,3R)-4-[(3aR,7aS...)
Affinity DataIC50: 0.280nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285969([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 0.280nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285976([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 0.400nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM313(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 0.400nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285980(LY-326188 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylc...)
Affinity DataIC50: 0.420nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM322(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 0.420nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM314(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 0.75nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285977([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 0.75nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285982([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 0.950nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM321((2S,3S)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50: 0.950nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM519(SQV | Invirase | CHEMBL114 | Ro 31-8959 | Fortovas...)
Affinity DataIC50: 1nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285975([(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6-tert-butylcarb...)
Affinity DataIC50: 1.30nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM320(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 1.30nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM312(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 1.40nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285970([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 1.40nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285974([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 1.70nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM308(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 1.70nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285979([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 2nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM309(hydroxyethylene isostere | (3R)-1,1-dioxo--thiolan...)
Affinity DataIC50: 2nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285978([(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6-tert-butylcarb...)
Affinity DataIC50: 2.60nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM319(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 2.60nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM317(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 2.60nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285972([(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6-tert-butylcarb...)
Affinity DataIC50: 2.60nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285981([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 3nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM307(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 3nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285968([1-Benzyl-3-(3-tert-butylcarbamoyl-octahydro-isoqu...)
Affinity DataIC50: 4.30nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM316((2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50: 4.30nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285967([(1R,2R)-3-((3aR,6S,7aS)-6-tert-Butylcarbamoyl-hex...)
Affinity DataIC50: 5.20nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM311(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 5.20nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285973([1-Benzyl-3-(3-tert-butylcarbamoyl-octahydro-isoqu...)
Affinity DataIC50: 8.10nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM315(hydroxyethylene isostere | hydroxyethylamine isost...)
Affinity DataIC50: 8.10nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM532(N- tert-butyldecahydro-2-[2(R)-hydroxy-4-phenyl-3(...)
Affinity DataIC50: 10nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM310(hydroxyethylene isostere | Sulfone Deriv. 8 | hydr...)
Affinity DataIC50: 10nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2004
Entry Details Article