Compile Data Set for Download or QSAR
Report error Found 101 Enz. Inhib. hit(s) with all data for entry = 50023566
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665110BDBM50665110(CHEMBL6170958)
Affinity DataIC50: 0.0770nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665110BDBM50665110(CHEMBL6170958)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665109BDBM50665109(CHEMBL6152892)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126500BDBM126500(US8778951, 310 | US11591322, Compound NVP-2)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of CDK9 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27566BDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 112464BDBM112464(US8623885, 5)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021574BDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665109BDBM50665109(CHEMBL6152892)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665116BDBM50665116(CHEMBL6177553)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PARP-1 (unknown origin) incubated for 60 mins by chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001584BDBM50001584(CHEMBL3237442 | US8841312, 1)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001544BDBM50001544(CHEMBL3237709)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001538BDBM50001538(CHEMBL3237703)
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001544BDBM50001544(CHEMBL3237709)
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5446BDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001545BDBM50001545(CHEMBL3237710)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209932BDBM209932(Veliparib | 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-be...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of GST-tagged PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169892BDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29589BDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 112464BDBM112464(US8623885, 5)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7392BDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001545BDBM50001545(CHEMBL3237710)
Affinity DataIC50: 4nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27566BDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209932BDBM209932(Veliparib | 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-be...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of hexa-Histidine-tagged PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665117BDBM50665117(CHEMBL6170658)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001538BDBM50001538(CHEMBL3237703)
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169892BDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665119BDBM50665119(CHEMBL6162969)
Affinity DataIC50: 7nMAssay Description:Inhibition of human CDK4 extracted from baculovirus infected Sf9 insect cells incubated for 1 hrs in presence of ATP by liquid scintillation counter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665118BDBM50665118(CHEMBL6175521)
Affinity DataIC50: 8nMAssay Description:Inhibition human recombinant FLT3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665117BDBM50665117(CHEMBL6170658)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK6 (unknown origin))More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7392BDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 10nMAssay Description:Inhibition CDK1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 148264BDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665118BDBM50665118(CHEMBL6175521)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CDK4 extracted from baculovirus infected Sf9 insect cells incubated for 1 hrs in presence of ATP by liquid scintillation counter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAurora kinase A(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Aurora A (unknown origin) by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665119BDBM50665119(CHEMBL6162969)
Affinity DataIC50: 11nMAssay Description:Inhibition human recombinant FLT3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139991BDBM139991(US8901140, 5 | US9358227, 5)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001584BDBM50001584(CHEMBL3237442 | US8841312, 1)
Affinity DataIC50: 14nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAurora kinase B(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B (unknown origin) by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665105BDBM50665105(CHEMBL6163941)
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526794BDBM50526794(CHEMBL4303287 | US10787436, Compound I-18)
Affinity DataIC50: 19nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665114BDBM50665114(CHEMBL6176188)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR (unknown origin) using Poly (Glu, Tyr) as substrate incubated for 60 mins in presence of ATP by Kinase-Glo Plus luminescence kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193086BDBM50193086(CHEMBL3969723)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169892BDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210177BDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 22nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
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