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Found
39
Enz. Inhib. hit(s) with all data for entry = 50023323
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.20nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.60nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.70nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71843
(US11724992, Example 307 | US11724992, Compound 366...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71731
(US11724992, Example 200 | US11724992, Compound 106...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71734
(US11724992, Example 203 | US11724992, Compound 136...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71735
(US11724992, Example 204 | US11724992, Compound 183...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612377
(N'-(1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612380
(N'-(1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612305
(US11724992, Example 6 | US11724992, Compound 102)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71832
(US11724992, Example 296 | US11724992, Compound 364...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 41nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71843
(US11724992, Example 307 | US11724992, Compound 366...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71223
(US11724992, Example 94 | US11724992, Compound 186b)
Copy SMILES
Copy InChI
Affinity Data
IC50: 96nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661894
(CHEMBL6146145)
Copy SMILES
Affinity Data
IC50: 120nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71735
(US11724992, Example 204 | US11724992, Compound 183...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 130nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612315
(BDBM612401 | BDBM612402 | N'-(1,2,3,5,6,7-hexahydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 137nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661897
(CHEMBL6151066)
Copy SMILES
Affinity Data
IC50: 170nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
IC50: 181nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71832
(US11724992, Example 296 | US11724992, Compound 364...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 190nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661896
(CHEMBL6173539)
Copy SMILES
Affinity Data
IC50: 210nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661894
(CHEMBL6146145)
Copy SMILES
Affinity Data
IC50: 210nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50155926
(CHEMBL3183703)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661895
(CHEMBL6168722)
Copy SMILES
Affinity Data
IC50: 270nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71731
(US11724992, Example 200 | US11724992, Compound 106...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 300nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661898
(CHEMBL6169554)
Copy SMILES
Affinity Data
IC50: 340nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661898
(CHEMBL6169554)
Copy SMILES
Affinity Data
IC50: 520nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50661897
(CHEMBL6151066)
Copy SMILES
Affinity Data
IC50: 670nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71736
(US11724992, Example 205 | US11724992, Compound 183...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 700nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50155926
(CHEMBL3183703)
Copy SMILES
Copy InChI
Affinity Data
IC50: 760nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM67549
(US11724992, Example 5 | US11724992, Compound 101)
Copy SMILES
Copy InChI
Affinity Data
IC50: 800nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71733
(US11724992, Example 202 | US11724992, Compound 136...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM50636753
(Emlenoflast | Inzomelid | Izd-174 | Izd174 | MCC-7...)
Copy SMILES
Affinity Data
IC50: 1.74E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM71202
(US11724992, Example 93 | US11724992, Compound 186a)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.50E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Copy reaction URL
Target
NACHT, LRR and PYD domains-containing protein 3
(Human)
IFM Therapeutics GmbH
Curated by
ChEMBL
Ligand
BDBM612304
(BDBM612305)
Copy SMILES
Copy InChI
Affinity Data
EC50: >3.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
Copy reaction URL