Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50023097
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650150BDBM50650150(CHEMBL4516422)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573115BDBM50573115(CHEMBL4865238)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells assessed as inhibition of AITC-induced intracellular Ca2+ flux by fluorescence dye based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241426BDBM50241426(3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-3,4-dihydrop...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331290BDBM50331290(N-(3-aminopropyl)-2-(3-methylbenzyloxy)-N-(thiophe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human TRPM8 in HEK293 cells in presence of methanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659084BDBM50659084(CHEMBL6148526)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human recombinant TRPM8 stably transfected in HEK293 cells assessed as inhibition of intracellular Ca2+ flux incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659084BDBM50659084(CHEMBL6148526)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659087BDBM50659087(CHEMBL6161199)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rat TRPM8 transfected in HEK293T cells assessed as reduction in intracellular Ca2+ level Fluo-4 dye based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659087BDBM50659087(CHEMBL6161199)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as inhibition of intracellular Ca2+ level by Fluo-4 dye based fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25525BDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293T cells assessed as inhibition of AITC-induced current by whole cell patch clamp analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613651BDBM50613651(CHEMBL5281182)
Affinity DataEC50:  45nMAssay Description:Agonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659090BDBM50659090(CHEMBL1610544)
Affinity DataEC50:  45nMAssay Description:Antagonist activity at TRPA1 (unknown origin) transfected in HEK293F cells assessed as reduction in intracellular Ca2+ by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659084BDBM50659084(CHEMBL6148526)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659088BDBM50659088(CHEMBL6143379)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at recombinant TRPA1 (unknown origin) expressed in T-REx-293 cells assessed as inhibition of AITC-induced intracellular Ca2+ flux...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659083BDBM50659083(CHEMBL6144304)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human recombinant TRPM8 stably transfected in HEK293 cells assessed as inhibition of intracellular Ca2+ flux incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659083BDBM50659083(CHEMBL6144304)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659086BDBM50659086(CHEMBL6150547)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659089BDBM50659089(CHEMBL465242)
Affinity DataEC50:  2.60E+3nMAssay Description:Antagonist activity at TRPA1 (unknown origin) expressed in HEK293 cells assessed as inhibition of AITC-induced intracellular Ca2+ flux by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659085BDBM50659085(CHEMBL6171037)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542904BDBM50542904(SESAMIN | CHEBI:66470)
Affinity DataIC50: 9.78E+3nMAssay Description:Antagonist activity at TRPM8 (unknown origin) in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318482BDBM50318482(CHEMBL470670 | l-menthol | (-)-menthol | MENTHOL |...)
Affinity DataEC50:  2.00E+5nMAssay Description:Agonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)