Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50022072
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50592747(CHEMBL5195904)
Affinity DataIC50: 0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50518965(CHEMBL4443062)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647813(CHEMBL5597724)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581524(CHEMBL5078405)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581523(CHEMBL5092943)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581522(CHEMBL5075273)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581522(CHEMBL5075273)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50: 0.460nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581524(CHEMBL5078405)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581524(CHEMBL5078405)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647810(Zotizalkib | Tpx 0131 | Tpx-0131 | TPX-0131 | TPX0...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647811(Zidesamtinib | Nvl-520 | NU-0002362 | NU-0002362-0...)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581523(CHEMBL5092943)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50546200(Vecabrutinib | Sns-062 | BIIB-062 | BSK-4841 | FP-...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647810(Zotizalkib | Tpx 0131 | Tpx-0131 | TPX-0131 | TPX0...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM144333(US8969336, 577 | US12350272, Compound ASP2215)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647812(Ff-10101 | FLT3-IN-1)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM537926(US11248003, Example 1)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNT-3 growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647814(CHEMBL5591124)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647809(CHEMBL5596270)
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647812(Ff-10101 | FLT3-IN-1)
Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50468192(CHEMBL4294743)
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50468192(CHEMBL4294743)
Affinity DataIC50: 6.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581522(CHEMBL5075273)
Affinity DataIC50: 8.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50581523(CHEMBL5092943)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM537979(US11248003, Example TRE-069)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50546200(Vecabrutinib | Sns-062 | BIIB-062 | BSK-4841 | FP-...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50500356(CHEMBL3747406 | US11066363, Compound 7)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647812(Ff-10101 | FLT3-IN-1)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50468244(CHEMBL4284413)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50518964(CHEMBL4474196)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM144333(US8969336, 577 | US12350272, Compound ASP2215)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNT-3 growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 48nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50500356(CHEMBL3747406 | US11066363, Compound 7)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM144333(US8969336, 577 | US12350272, Compound ASP2215)
Affinity DataIC50: 117nMMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 381nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50518964(CHEMBL4474196)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed