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Found
13
Enz. Inhib. hit(s) with all data for entry = 50022192
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM50649225
(CHEMBL5618643)
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Copy InChI
Affinity Data
IC50: 0.844nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
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PubMed
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Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM50300690
(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
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Copy InChI
Affinity Data
IC50: 1.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM185149
(Crenolanib | 1-[2-[5-[(3-methyloxetan-3-yl)methoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM185149
(Crenolanib | 1-[2-[5-[(3-methyloxetan-3-yl)methoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM16673
(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM50300690
(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM185149
(Crenolanib | 1-[2-[5-[(3-methyloxetan-3-yl)methoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Histone deacetylase 1
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM50649225
(CHEMBL5618643)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM16673
(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM4814
(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM16673
(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 104nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM4814
(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Ain Shams University
Curated by
ChEMBL
Ligand
BDBM50326053
(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 528nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL